The goal of this meeting is to bring together leading experts in the field of intrinsically disordered proteins to discuss the implementation of the IDP Ensemble Benchmarking Challenge (IDP-Bench).

IDP-Bench is envisioned as a recurring, community-driven initiative to establish open, transparent, and standardized benchmarking for IDP ensemble prediction. This effort will follow a biennial four-phase cycle aligned with CAID, involving:

1. Selection and curation of high-quality experimental datasets by an independent committee,
2. Submission of ensemble predictions by participating groups,
3. Automated, multi-metric scoring against withheld validation data, and
4. Continuous dissemination of results via a dedicated open-access platform.

This workshop in Seville will provide the opportunity to:

• Define the scope, procedures, and timeline of IDP-Bench,
• Discuss dataset selection and evaluation metrics,
• Build consensus on community involvement and governance,
• Set the foundation for the first benchmarking cycle.