Non-globular proteins in the era of Machine Learning
COST Action CA21160
CONFERENCE
4TH ML4NGP MEETING on Machine Learning and Non-globular proteins
May 19-22, 2026
Warsaw, Poland
welcome message
Welcome to the ML4NGP Meeting 2026!
We are delighted to invite you to the 4th and final main meeting of our COST Action ML4NGP, taking place 19–22 May 2026 in the vibrant and historic city of Warsaw, Poland.
As the last major gathering of our Action, this meeting is of exceptional importance to all of us who have contributed to the growth, energy, and scientific excellence of ML4NGP over the past years. It is a moment to celebrate our achievements, strengthen collaborations, and reflect on the impact our network has had on the research community.
This conference will once again bring together experts, young researchers, and innovators working at the intersection of Non-Globular Proteins (NGPs) and Machine Learning. Participants will have the opportunity to explore and discuss the latest developments in:
- Cutting-edge bioinformatic tools and specialised databases
- Research on repeats, intrinsically disordered regions, and low-complexity regions
- Studies of proteins prone to aggregation or phase separation
Whether you have been part of ML4NGP from the beginning or joined along the way, this meeting offers an exceptional platform to present your work, engage in thought-provoking discussions, and strengthen scientific connections that hopefully will continue long after the Action.
We warmly invite you to Warsaw to commemorate this milestone and to help shape the future directions of our community.
We look forward to welcoming you to this meaningful and memorable event!
Discover more about Warsaw city at go2warsaw.pl
confirmed speakers
KEYNOTE SPEAKERS
Prof. Rohit Pappu
Washington Univ. in St. Louis
USA
Prof. Ben Schuler
University of Zurich
Switzerland
Prof. Andrea Sinz
University of Halle-Wittenberg
Germany
Prof. Tuomas Knowles
University of Cambridge
UK
INVITED SPEAKERS
Dr. Michael Heinzinger
Technische Universität München
Germany
Prof. Magnus Kjærgaard
Aarhus University
Denmark
Dr. Milot Mirdita
Sungkyunkwan University School of Medicine
Korea
Dr. Michal Sharon
Weizmann Institute of Science
Israel
Prof. Andrey Kajava
Université Montpellier
France
Prof. Michael Feig
Michigan State University
USA
Prof. Salvador Ventura
IBB-UAB
Spain
Prof. Miguel Andrade
Johannes-Gutenberg University in Mainz
Germany
Prof. Sonia Longhi
CNRS
France
Prof. Turkan Haliloglu
Boğaziçi University
Turkey
Prof. Cláudio Gomes
Faculdade Ciências Universidade de Lisboa
Portugal
|
|
Deadline |
Status |
|
Abstract submission open |
December 08, 2025 |
Closed |
|
Abstract submission deadline (posters & talks) |
New date: March 15, 2026 |
Closed |
|
Abstract decision |
March 19, 2026 |
Closed |
|
Registration and Meal Fee payment |
April 26, 2026 |
Closed |
|
Conference dates |
19-22 May 2026 |
Confirmed |
Registration is open until 26 April and is mandatory for all participants.
Meal fee is 200 EUR/860 PLN including all lunches, welcome reception and social dinner.
Payment must be made only by bank transfer after completing the registration form, by April 26, 2026.
BANK ACCOUNT DETAILS FOR PAYMENT:
- Account holder: Instytut Biochemii i Biofizyki Polskiej Akademii Nauk
- Account holder address: Pawinskiego 5a, 02-106 Warszawa
- Bank: Bank Gospodarstwa Krajowego
- Bank address: Al. Jerozolimskie 7, 00-955 Warszawa
- IBAN: PL43 1130 1017 0020 1464 2520 0065
- Swift code: GOSKPLPW
Participants involved in the ML4NGP COST Action who have been selected to deliver talks will be eligible for travel fellowships in accordance with COST reimbursement rules. A daily allowance of 200 EUR will help to support costs with local transportation, accommodation, and food expenses. Additionally, long travel expenses (e.g., plane tickets) will be reimbursed separately.
Participants from ML4NGP COST Action with selected abstracts for posters will also benefit from the travel fellowship on a best effort basis.
information
Presentation time
Keynote lectures | Speaking time is 35 minutes plus 5 minutes discussion.
Invited talks | Speaking time is 25 minutes plus 5 minutes discussion
Selected talks | Speaking time is 12 minutes plus 3 minutes discussion.
Flash posters | Speaking time is 5 minutes.
Poster presenters are requested to set up their posters in the designated area before each poster session starts. Presenters are expected to be available near their posters during the assigned session.
Number of poster stands: 45
Poster size: A0 size – 118.9 cm x 84.1 cm (length x width)
Speakers are required to have their presentation ready on a USB key.
Your slides should be either in .pdf, .ppt or .pptx format.
Venue
LOCATION
The ML4NGP Meeting 2026 will take place in the historiacal city of Warsaw.
VENUE
The ML4NGP Meeting 2026 will take place at Targowa Creativity Centre in Warsaw.
Address: Targowa 56, 03-733 Warsaw, Poland.
CONFERENCE PROGRAM
Preliminary Program
Tuesday, May 19
08:00-09:00
Registration
09:00-09:15
Welcome Note
Overview of ML4NGP COST Action | Alexander Monzon
09:15-09:55
Keynote Talk
Phase transitions of RNA binding NGPs | Rohit Pappu
09:55-10:25
Invited Talk
Beyond static structures: how protein language models help understanding protein flexibility | Michael Heinzinger
10:25-10:40
Selected Talk
Generative design of intrinsically disordered proteins based on conditioned protein language models | Juan Cortes
10:40-11:10
Coffee Break
11:10-11:40
Invited Talk
Peptide dynamics inside condensates on different scales | Michael Feig
11:40-11:55
Selected Talk
Variant Effect Predictors in Intrinsically Disordered Regions are Systematically Biased | Zsuzsa Dosztanyi
11:55-12:10
Selected Talk
Disordered and not so disordered proteins in bacterial biofilms | Dirk Linke
12:10-12:25
Selected Talk
IDR-Mediated Nucleosome Engagement by the Pioneer Factor Sox2 | Sveinn Bjarnason
12:30-14:30
Lunch
14:30-15:10
Keynote Talk
Probing the Rapid Interaction Dynamics of Charged Disordered Proteins | Ben Schuler
15:10-15:25
Selected Talk
Achieving predictive all-atom simulations of disordered proteins and their condensates | Miloš Ivanovič
15:25-15:40
Selected Talk
Intrinsically disordered regions in mycobacterial transcription | Lukas Zidek
15:40-15:55
Selected Talk
Switch from a fuzzy to an ordered binding mode in the disordered regulator HigA2 mediates a ratio-sensing autroregulatory gene circuit | San Hadzi
15:55-16:55
Flash Poster Presentations
17:00-20:00
Welcome Reception
Wednesday, May 20
08:30-09:00
Registration
09:00-09:40
Keynote Talk
Characterization of Intrinsically Disordered Proteins by Cross-Linking Mass Spectrometry | Andrea Sinz
09:40-10:10
Invited Talk
Intrinsically Disordered Proteins Shape Organ-Specific Aging Trajectories | Michal Sharon
10:10-10:25
Selected Talk
Ion mobility mass spectrometry unveils global protein conformations in response to conditions that promote and reverse protein phase separation | Rebecca Beveridge
10:25-11:00
Coffee Break
11:00-11:40
Keynote Talk
Biophysical insights into IDP phase behaviour | Tuomas Knowles
11:40-12:10
Invited Talk
Intrinsic disorder and fibril formation by the Henipavirus W proteins: molecular grammar and functional impact | Sonia Longhi
12:10-12:25
Selected Talk
Structure-function studies of iron mineralization in extreme IDP confinement | Raz Zarivach
12:30-14:00
Lunch
14:00-16:00
Round Table
16:00-16:30
Coffee Break
16:30-18:00
Poster Session 1
18:30
Tour Warsaw historic city centre (optional)
Thursday, May 21
08:30-09:00
Registration
09:00-09:30
Invited Talk
Molecular Models of Brain-Derived α-Synuclein Fibrils Reveal a Fuzzy-Coat-Mediated Mechanism for Selective Peptide Binding | Salvador Ventura
09:30-10:00
Invited Talk
Chaperone-mediated regulation of tau phase separation | Claudio Gomes
10:10-10:30
Invited Talk
Beta-Arches as a Key Element in Improving Structure-Based and Machine-Learning Predictors of Amyloid Formation | Andrey Kajava
10:30-11:10
Coffee Break
11:10-11:25
Selected Talk
Amyloid Proteins Through the Lens of AI Prediction Tools | Malgorzata Kotulska
11:25-11:40
Selected Talk
Systematic mutational mapping reveals optimal amyloid formation for RIPK function | Mariano Martín
11:40-11:55
Selected Talk
TMcluster: Nuanced clustering of protein structures using similarity matrices and dimensionality reduction | Oriol Bárcenas
11:55-12:10
Selected Talk
Local frustration analysis reveals the energetic landscape of intrinsic disorder | Franco Simonetti
12:10-12:25
Selected Talk
Exon-Informed Multiple Sequence Alignments for Enhanced Coevolution Signal Detection on Intrinsically Disordered Proteins | Diego Zea
12:30-14:30
Lunch
14:30-15:00
Invited Talk
AI‑based protein analysis from multimers to metagenomes | Milot Mirdita
15:00-15:30
Invited Talk
Order within intrinsically disordered regions: function, structure and evolution | Miguel Andrade
15:30-15:45
Selected Talk
Zero-Shot Prediction of Thermodynamic Properties of Proteins | Gabor Erdos
15:45-16:00
Selected Talk
Machine Learned Coarse-Graining of Non-Globular Proteins | Andrea Guljas
16:00-16:30
Coffee Break
16:30-18:00
Poster Session 2
19:00-22:00
Social Dinner
Friday, May 22
09:45-10:15
Invited Talk
Intrinsic disorder in the age of protein design | Magnus Kjaergaard
10:15-10:30
Selected Talk
Generating conformational ensembles of multidomain proteins with flexible regions from AlphaFold models using AFflecto | Matyas Pajkos
10:30-11:00
Coffee Break
11:00-11:30
Invited Talk
Physics-Guided Diffusion Sampling for Conformational Variability | Turkan Haliloglu
11:30-11:45
Selected Talk
MAPPIE: Map of Protein-Protein Interaction Embeddings for Functional Discovery | Mert Cihan
11:45-12:00
Selected Talk
Large-scale proteomics and Deep learning for the generation of protein-protein interaction (PPI) maps at atomic resolution | Jinmei Gao
12:00-12:15
Selected Talk
WormLink: A Tool for Engineering Synthetic Spacer Regions | Laura Gherman
12:15-12:30
Closing Remarks
12:30-14:00
Lunch
ORGANIZATION
LOCAL ORGANIZING COMMITTEE
Marcin Grynberg, Katarzyna Jagiello-Wilgat, Dorota Święcicka (Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland)
SCIENTIFIC COMMITTEE
Core Group of ML4NGP COST Action
contact information
Information and inquiry: info@ml4ngp.eu
PATRONAGES
local PARTNERS AND SPONSORS
This event is part of the activities of the COST Action ML4NGP, CA21160, supported by COST (European Cooperation in Science and Technology).